Description
Composition: Each bolus contains
Trimethoprim IP 200 mg
Sulphadiazine IP 1 g
Trimethoprim potentiates the antimicrobial activity of sulfonamides to produce a remarkable synergistic effect so that antimicrobial efficiency can be obtained with very low levels of the drug combination.
Antibacterial spectrum
Sulphadiazine is active against gram-negative and gram-positive organisms, including Actinomyces , Bordetella, Clostridium, Corynebacterium , Fusobacterium , Haemophilus , Klebsiella , Pasteurella , Proteus , Salmonella , Shigella , and Campylobacter spp , as well as Escherichia coli, streptococci, and staphylococci.
Indications
- Gastrointestinal infections
- Respiratory infections
- Genital infections
- Urinary tract infections
- Mastitis
Contraindication
Trimethoprim / sulfadiazine should not be used in horses showing marked liver parenchymal damage, blood dyscrasias or in those with a history of sulfonamide sensitivity.
Administration and dosage
Trimethoprim / sulphadiazine 15-60 mg / kg body wt.
Vetran –LA 1 bolus / 80 kg body wt. twice daily
Presentation
Strips of 4 bolli
